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Titlebook: Immunotoxin Methods and Protocols; Walter A. Hall Book 2001 Humana Press 2001

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發(fā)表于 2025-3-27 00:13:23 | 只看該作者
32#
發(fā)表于 2025-3-27 03:38:12 | 只看該作者
Synthesis of Monensin Derivatives and Their Effect on the Activity of Ricin A-Chain Immunotoxinsly in solid tumor treatment (.). The cytotoxic activity of RTA conjugates can be potentiated in vitro by lysosomotropic amines (e.g., NH.Cl, chloroquine, methylamine, amantadine), ionophores (e.g., monensin, nigericin, lasalocid), or lysosomal enzyme inhibitors (e.g., leupeptin, pepstatin) (.-.).
33#
發(fā)表于 2025-3-27 08:33:34 | 只看該作者
Comparison of Immunotoxins Bearing a Single Saporin Molecule with Multiple Toxin Conjugatesective antigen expressing target cell (., .). While this has been shown to be generally true for IT performance in vitro, the same has not been consistently demonstrable in vivo. For instance, Ghetie et al. have shown that anti-CD19 and anti-CD25 ricin A-chain (RTA) ITs containing two RTA moieties p
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發(fā)表于 2025-3-27 12:01:38 | 只看該作者
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發(fā)表于 2025-3-27 14:20:35 | 只看該作者
Tyrosine Kinase Inhibitors Against EGF Receptor-Positive Malignanciesme family as EGFR) at nanomolar levels. EGF-genistein (EGF-gen) is an EGFR-binding cytotoxic agent that also shows potency in the nanomolar range (., .) and will be discussed in this chapter. The search for new small molecules that inhibit kinases has involved traditional approaches, including the t
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發(fā)表于 2025-3-27 19:41:07 | 只看該作者
37#
發(fā)表于 2025-3-28 01:12:03 | 只看該作者
Effects of Selective Immunotoxic Lesions on Learning and Memorygic neurons at the lesion site (.). This lesion method has been employed to create an animal model of the degeneration of basal forebrain cholinergic neurons seen in patients with Alzheimer’s disease (.). Such a model has been impossible to achieve with other lesion methods that do not produce selec
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發(fā)表于 2025-3-28 02:38:07 | 只看該作者
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發(fā)表于 2025-3-28 09:55:44 | 只看該作者
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發(fā)表于 2025-3-28 14:30:19 | 只看該作者
lier he received cefixime to treat a bronchitis but after few days the symptoms had worsened with the onset of fever, purulent ocular discharge, stomatitis and erosions to the labial mucosa with difficulty in feeding. Acyclovir and nystatin were started without improvement and at the admission the p
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