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Titlebook: Immunotoxin Methods and Protocols; Walter A. Hall Book 2001 Humana Press 2001

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發(fā)表于 2025-3-21 18:06:07 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)Immunotoxin Methods and Protocols
編輯Walter A. Hall
視頻videohttp://file.papertrans.cn/463/462320/462320.mp4
概述Includes supplementary material:
叢書(shū)名稱(chēng)Methods in Molecular Biology
圖書(shū)封面Titlebook: Immunotoxin Methods and Protocols;  Walter A. Hall Book 2001 Humana Press 2001
描述Immunotoxins represent a new class of human therapeutics that have widespread applications and a potential that has not yet been fully recognized since they were first conceived of by Paul Ehrlich in 1906. The majority of advances in the development and implementation of immunotoxins has occurred over the last 20 years. The reasons for this use of immunotoxins in basic science and clinical research are the powerful concurrent advances in genetic engineering and receptor physiology. Recombinant technology has allowed investigators to produce sufficient quantities of a homogeneous c- pound that allows clinical trials to be performed. The identification of specific receptors on malignant cell types has enabled scientists to generate immunotoxins that have had positive results in clinical trials. As more cellular targets are identified in coming years, additional trials will be conducted in different disease states affecting still larger patient populations. Modulation of the immune system to decrease the humoral response to immunotoxins may improve their overall efficacy. As increasingly more effective compounds are generated, it will be necessary to decrease the local and systemic to
出版日期Book 2001
版次1
doihttps://doi.org/10.1385/1592591140
isbn_softcover978-1-61737-183-7
isbn_ebook978-1-59259-114-5Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2001
The information of publication is updating

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Walter A. HallIncludes supplementary material:
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Methods in Molecular Biologyhttp://image.papertrans.cn/i/image/462320.jpg
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Book 2001e they were first conceived of by Paul Ehrlich in 1906. The majority of advances in the development and implementation of immunotoxins has occurred over the last 20 years. The reasons for this use of immunotoxins in basic science and clinical research are the powerful concurrent advances in genetic
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Development and Activities of the BR96-Doxorubicin Immunoconjugate also been obtained when a MAb reacting with a differentiation antigen expressed on colorectal carcinomas was given to patients who were at high risk of tumor recurrence following primary surgery (.).
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CD7-Specific Single Chain Fv Immunotoxinsrticipates in the development or migration of murine NK1.1. T-cells in the liver, and that reduced numbers of these cells results in decreased cytokine production elicited by bacterial lipopolysaccharides.
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Bispecific Monoclonal Antibodies for the Targeting of Type I Ribosome-Inactivating Proteins Against hey lack a lectin B-chain for cell entry, and thus have a low toxicity for whole cells. Type I RIPs such as saporin can be easily purified (.) and have been successfully used to generate potent ITs, displaying antitumor activity both in vitro (.) and in vivo (.).
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