Titlebook: Immune Deficiency and Cancer; Epstein-Barr Virus a David T. Purtilo Book 1984 Plenum Publishing Corporation 1984 antigen.cancer.cancer regi

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Expression of Virus-Associated Functions in Cells Transformed , by Epstein-Barr Virus: Epstein-Barr sformation assay (1–5). This virus also infects B lymphocytes .; up to 20% of the peripheral B cells in patients with infectious mononucleosis (IM) express an EBV-associated nuclear antigen, EBNA (6), When peripheral lymphocytes from IM patients are collected and cloned directly in soft agar, some B

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Relationship of Immune Deficiency and Oncogenic Viruses to Malignant B Cell Lymphomas: Mouse and Mans (EBV)-induced polymorphic B cell lymphoma in immunodeficient patients, it is apparent that the vast majority of spontaneously occurring B cell lymphomas in immunodef icient mice and men are . causally linked to overt inducing agents (e.g., oncogenic viruses) (Table 1). For this reason, the compara

Microaneurysm

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Lymphoma in Cardiac Transplant Recipients Associated with Cyclosporin A, Prednisone and Anti-Thymocyrecipients successful outcome of the procedure has been highly dependent upon effective management of allograft rejection using immunosuppressive agents. Prior to 1980 these agents included Azathioprine, corticosteroids and antithymocyte globulin — ATG (conventional therapy). In 1980 cyclosporin A,

PAGAN

Lymphoproliferative Diseases in Renal Allograft Recipientsiduals with genetically determined immunodeficiency or autoimmune diseases, and patients following chemotherapy or radiation therapy (20, 35, 36, 46). Because of their histological features and clinical aggressiveness, these lymphoproliferations have been labelled malignant lymphomas in renal allogr

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Chronic Mononucleosisbecome a common archetype of human latent viral infections (3). This has been ascribed to its infection of B lymphocytes (4) and a resultant permanent viral carrier state (3). These genome carrying cells may give rise to continuous EBV-containing lymphoblastoid cell lines in . cultures established f

Mammal

The Syndrome of Acquired Immunodeficiency Among a Subset of Homosexual Menity, San Francisco and Los Angeles remains unexplained. Manifestations of the syndrome include opportunistic infections, autoimmunity, chronic lymphadenomegaly, and malignancies. The syndrome has no acceptable established diagnostic definition. The multiple diverse mainifestations are an essential f