Titlebook: Immune Deficiency and Cancer; Epstein-Barr Virus a David T. Purtilo Book 1984 Plenum Publishing Corporation 1984 antigen.cancer.cancer regi

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Biology of Epstein-Barr Virusridization with biopsy materials (for review see ref. 2). The work of many laboratories contributed data which does not seem to fit into a unifying concept. This paper briefly summarizes some apparently conflicting results; from these data a hypothetical model for the biology of EBV is developed.

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Relationship of Immune Deficiency and Oncogenic Viruses to Malignant B Cell Lymphomas: Mouse and Manomas in immunodef icient mice and men are . causally linked to overt inducing agents (e.g., oncogenic viruses) (Table 1). For this reason, the comparative features of dualtropic MuLV-induced and EBV-induced B cell diseases are discussed, as well as the association of B cell lymphomas with congenital and acquired immunodeficiencies.

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Burkitt’s Lymphomafor modern chemotherapy programs. Finally, BL is unique in its histopathologic, immunologic, and cytogenetic attributes. The surface markers studies of BL have demonstrated arrested lymphocyte differentiation. Other cancers are viewed also in the context of blocked autogeny.

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Chronic Mononucleosisscence), the recognized tendency of herpes viruses to reactivation (3), the persistent carrier state, and the predisposition to atypical infections, it might be expected that recurrent or prolonged atypical EBV infections would be commonly reported.

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Lymphoproliferative Diseases and Kaposi’s Sarcoma in Homosexual Malese homosexual community has implied a transmissible agent is responsible for AIDS (12). A viral etiology seems most plausible. The possibility of an underlying genetic predisposition to aberrant handling of a common viral infection is reminiscent of the model of Purtilo’s X-linked lymphoproliferative

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David T. Purtilom. Such imagined binaries are also shown to play into spatial and geographical configurations. This is illustrated through drawing on a tenth-century monograph by the scholar al-Nisabūri whose little book . (in translation: The Wise Madmen) has never been translated from Arabic in its entirety and y

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