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Titlebook: HDL Deficiency and Atherosclerosis; G. Assmann Book 1995 Kluwer Academic Publishers 1995 Lipoprotein.atherosclerosis.cardiovascular.corona

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發(fā)表于 2025-3-21 16:16:13 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱HDL Deficiency and Atherosclerosis
編輯G. Assmann
視頻videohttp://file.papertrans.cn/421/420178/420178.mp4
叢書名稱Developments in Cardiovascular Medicine
圖書封面Titlebook: HDL Deficiency and Atherosclerosis;  G. Assmann Book 1995 Kluwer Academic Publishers 1995 Lipoprotein.atherosclerosis.cardiovascular.corona
描述The tandem pace of medical knowledge and prevention of ischaemic heart disease over the past 50 years is testimony to the effectiveness of a combination of massive scientific research, continuous transfer of the results to medical practice, community actions and population aware- ness. The death rate from coronary heart disease in the United States rose 20% from 1950 to 1963, when a dramatic and steady downward inflection began, arriving today at a rate over 50% lower. Numerous factors have contributed to this success. By 1950 lipoproteins had just been discovered, but a decade later a great surge in research had focussed upon plasma cholesterol and lipoprotein concentrations as major predictors of risk. Today, a continuing expansion and sophistica- tion of that research has removed all doubt about the significance of particular patterns. The pathway to ideal prophylaxis, however, particu- larly for risks associated with inherited lipoprotein disorders, still awaits the untangling of great amounts of new information that continue to rise from application of molecular technology. This volume deals with many of the contemporary puzzles. One theme revolves about the high density lipop
出版日期Book 1995
關(guān)鍵詞Lipoprotein; atherosclerosis; cardiovascular; coronary heart disease; gene therapy; genetics; heart; heart
版次1
doihttps://doi.org/10.1007/978-94-011-6585-3
isbn_softcover978-94-011-6587-7
isbn_ebook978-94-011-6585-3Series ISSN 0166-9842
issn_series 0166-9842
copyrightKluwer Academic Publishers 1995
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發(fā)表于 2025-3-22 00:06:09 | 只看該作者
Role of high density lipoprotein subclasses in reverse cholesterol transport,DL) cholesterol and the risk of myocardial infarction (reviewed in ref. 1). The ability of HDL to protect the vessel wall from atherosclerosis has usually been explained by the reverse cholesterol transport model (reviewed in ref. 2) in which HDL mediates the flux of excess cholesterol from peripher
板凳
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地板
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Intracellular cholesterol transport,nding the mechanisms involved in regulated, target-specific intracellular cholesterol transport is of great impact for understanding the pathogenesis of atherosclerosis and a number of inherited lipid storage disorders, such as Niemann-Pick disease (type C), Zellweger disease and Tangier disease. Si
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Gene therapy for the genetic dyslipoproteinaemias,idated. This new information provides a conceptual framework for understanding lipoprotein metabolism in normal subjects and patients with the genetic dyslipoproteinaemias. Schematic overviews of our current concepts of lipoprotein metabolism are illustrated in Figs. 1 and 2.
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