Titlebook: Evolutionary Dynamics of Malignancy; The Genetic and Envi Robert C. Jackson Book 2023 The Editor(s) (if applicable) and The Author(s), unde

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Implications of Evolutionary Dynamics for Cancer Treatment and Prevention,tially prevented by minimising exposure to radiation and chemical carcinogens, but there is a baseline amount of spontaneous chromosomal damage and genetic mutation, meaning that cancer can never be completely prevented. Although it may never be possible to prevent cancer initiation, many of the dea

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https://doi.org/10.1007/978-3-031-32573-1cancer evolution; evolutionary dynamics; mathematical modeling of cancer; computational models; cancer t

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Gerard A. J. M. Jagers op Akkerhuistes. The cellular environment exerts selective pressure on the cellular variants in the tumour population. Tumours have multiple biochemical abnormalities, but the most consistent changes relate to increased cell division. Decreased spontaneous cell death is also often seen. Loss of differentiated t

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Lecture Notes in Biomathematicsetic damage. Tumours are genetically unstable, such that the number of mutations and chromosomal abnormalities increases with time. Genetic and/or chromosomal instability is now regarded as the defining characteristic of cancer..Cancer genome projects, based upon whole genome sequencing, have identi

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Hot Issues of the Yangtze River,factors. The normal cell division cycle contains checkpoints that prevent a cell from progressing to the next phase if abnormalities (e.g. DNA damage) are present; the cell will not progress until the problem is corrected. If the damage cannot be corrected in a few hours, the damaged cell will under

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