Titlebook: Specificity and Function of Clonally Developing T Cells; Bernhard Fleischer,J?rg Reimann,Hermann Wagner Conference proceedings 1986 The Ed

認(rèn)識(shí)

The Change of Specificity, Karyotype, and Antigen-Receptor Gene Expression is Correlated in Cytotoxiove postulate. Because of that model character, the karyotypic and molecular genetic analysis of cytotoxic lymphocyte clones (CTLL) and their variants should hint at the genetic and molecular events involved in changes of specificity and function, cellular instability and ultimately malignant transformation.

泄露

Introductory Remarksfunctions. Consequently the function of the progeny of a single cell is being analyzed. This, however, puts constraints on the validity of the analysis, since cells have to be expanded in vitro under conditions which may or may not deter the functional potential present in the ancestor cells.

indigenous

Introductory Remarksnt the most easily identified precursor cells in the thymus, and for reasons made clear in the three following papers, are perhaps one of the most interesting in terms of the critical events of intrathymic T-cell differentiation. There was general agreement between speakers and discussers on most ar

Ascendancy

Development of T Lymphocytes Within the Thymus and Within Thymic Nurse Cellswhich may be steps along a developmental pathway. About 95% of adult murine thymic lymphocytes can be assigned to one of four discrete subpopulations as summarized in Table 1. These major subpopulations, and many of their surface markers, have been recognized for some time, and the recent applicatio

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Encumber

consolidate

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抱狗不敢前

Expression of T-Cell Receptor by a Mouse Monoclonal Antigen-Specific Suppressor T-Cell Lineo sub-units with an apparent M. of approximately 42K (A. et al. 1982; K. et al. 1983). The antigen-specific receptor expressed by human T lymphocytes displays a similar structure, but the two subunits, denominated α and β chain, have a M. of about 51K and 43K, respectively (M. et al. 1983; A. et al.

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