Titlebook: Signal Transduction in the Cardiovascular System in Health and Disease; Ashok K. Srivastava,Madhu B. Anand-Srivastava Book 2008 Springer-V

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Role of Hyperglycemia and Redox-Induced Signaling in Vascular Complications of Diabetesic oxide and increase the formation of peroxynitrite which may contribute to all of the hemodynamic and physiological changes occurring in diabetes. G-protein/adenylyl cyclase signaling that plays an important role in the regulation of cardiovascular functions has also been reported to be impaired i

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Regulatory Role of TGF-β in Cardiac Myofibroblast Function and Post-MI Cardiac Fibrosis: Key Roles od7 expression and altered intracellular c-Ski expression and/or distribution may contribute to chronic imbalance of R-Smad activation in classic TGF-β. signaling in the context of cardiac myofibroblast function. Thus, reduced and insufficient expression and activation of c-Ski and Smad7 may contribu

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Therapeutic Angiogenesis and Vasculogenesis for Ischemic Diseasetors by target tissues. Both cell therapy and gene therapy have proven to be effective in promoting neovascularization in various animal models. Although cell therapy alone is proven to be beneficial, the combination of cell and gene therapy may enhance therapeutic neovascularization. Thus, clinical

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