Titlebook: Sex Steroids‘ Effects on Brain, Heart and Vessels; Volume 6: Frontiers Roberta Diaz Brinton,Andrea R. Genazzani,John C. S Book 2019 Intern

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Estrogenic Regulation of Neuroprotective and Neuroinflammatory Mechanisms: Implications for Depresstion, synaptic plasticity, and neuroinflammation. In the aged brain and under neurodegenerative conditions, microglial cells acquire a senescent reactive phenotype, which involves a dysregulated inflammatory response that affects the normal function and metabolism of neurons and other cell types, in

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Adrenal Androgens Impact on Neurosteroids,rvous system. The available clinical and experimental findings support the critical role of neurosteroids during fertile life and reproductive aging and their relationship with endogenous and exogenous sex steroids. Protective steroid hormones such as dehydroepiandrosterone (DHEA) and particularly i

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Sex, Gender, and the Decline of Dementia, narrative review of new ideas and concepts related to the impact of sex and gender differences on the declining risk of dementia. In particular, I discuss three examples of risk factors related to sex and gender that have probably contributed to the trend. Apolipoprotein E genotype is equally commo

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Obstetric History and Cardiovascular Disease (CVD) Risk,o overcome these alterations may result in hypertensive pregnancy disorders (gestational hypertension, preeclampsia/eclampsia) or gestational diabetes mellitus. Recent studies have shown that these complications not only affect the pregnancy outcome but are also related to vascular dysfunction that

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