Titlebook: Rotaviruses; Methods and Protocol James Gray,Ulrich Desselberger Book 2000 Humana Press 2000

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Pathogenesis and Animal Models, dissect immune responses to RV (..). However, because older mice (>14 d) and rabbits are not susceptible to diarrhea after inoculation with either homologous (murine or lapine, respectively) or heterologous (human) RVs, assessment of protective immunity is restricted to prevention of virus shedding only (.–.).

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Epidemiology of Group A Rotaviruses Surveillance and Burden of Disease Studies,ly in developing countries (.). This chapter will describe the epidemiological features of Group A RV infections, and will critically review the current surveillance strategies used to define the burden of disease.

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Electron Cryomicroscopy and Computer Image Processing Techniques,eloped icosahedral virus. Once RV was recognized as a major human pathogen, it was extensively studied using modern molecular genetic and biological techniques, as discussed elsewhere in this book. These studies provided basic information about gene-coding assignments, protein processing, genome exp

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Virus Replication, and transcription of the RV genome, the assembly and structure of the rotavirion, and the structure and function of RV proteins. Because it is not possible to provide a detailed description of all the techniques developed, this chapter stresses only those that have broad application, or which repre

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