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Titlebook: Risk and Progression Factors in Carcinogenesis; H. K. Müller-Hermelink,H.-G. Neumann,W. Dekant Conference proceedings 1997 Springer-Verlag

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樓主: crusade
41#
發(fā)表于 2025-3-28 18:00:43 | 只看該作者
42#
發(fā)表于 2025-3-28 20:20:48 | 只看該作者
Oxidative DNA Damage Induced by Dioxetanes, Photosensitizing Ketones, and Photo-Fenton Reagents). Oxidative degradation of DNA causes mutations predominantly at GC base pairs to yield single base substitutions and G to T transversions (Piette 1991). Consequently, the DNA transformation efficiency is diminished and replication is inhibited.
43#
發(fā)表于 2025-3-29 00:23:24 | 只看該作者
Chemical Mechanisms of Formation of DNA-Carcinogen Adducts, Elucidation of Potential of Adducts for cancer related to occupational and incidental exposure to industrial chemicals is debatable, concerns about the development of cancer and birth defects from chemicals in the environment are very great among the public and deserve to beaddressed seriously.
44#
發(fā)表于 2025-3-29 05:37:21 | 只看該作者
Formation of Micronuclei and Inhibition of Topoisomerase II in the Comet Assay in Mammalian Cells wiequences of mammalian neoplasia and also occurs in cultured cells after treatment with certain carcinogenic drugs (Spruck et al. 1993). Changes in DNA methylation can affect DNA conformation (Bird 1992).
45#
發(fā)表于 2025-3-29 10:40:34 | 只看該作者
The Role of Raf Kinases in Development and Growth of Tumors cell surface receptors, (2) the receptors themselves, (3) intracellular signal transducers, and (4) transcription factors. Mutations of oncogenes leading to cancer frequently cause constitutive activity of the gene products. This results in an unregulated and enhanced transduction of mitogenic signals from the cell membrane to the nucleus.
46#
發(fā)表于 2025-3-29 15:17:53 | 只看該作者
47#
發(fā)表于 2025-3-29 18:17:25 | 只看該作者
48#
發(fā)表于 2025-3-29 21:21:44 | 只看該作者
49#
發(fā)表于 2025-3-30 03:46:49 | 只看該作者
Saccharomyces cerevisiaedeath or in transformation from quiescence to uncontrolled proliferation. Thus, the investigation of the cell cycle will lead to a better understanding of the molecular events which result in malignant cell growth.
50#
發(fā)表于 2025-3-30 06:55:06 | 只看該作者
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