Titlebook: Ribosomes; Alexander S. Spirin Book 1999 Springer Science+Business Media New York 1999 RNA.biology.biosynthesis.evolution.membrane.membran

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Protein Biosynthesisa complex asymmetric quaternary structure. In order to synthesize protein, the ribosome must be supplied with (1) a program determining the sequence of amino acid residues in the polypeptide chain of a protein, (2) the amino acid substrate from which the protein is to be made, and (3) chemical energ

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Ribosomal RNAubunits. The rRNA molecules form a framework for specific positioning of ribosomal proteins in the ribosome. rRNA plays the leading role in ribosome function, participating in every aspect of protein synthesis. Therefore, it can be said that the ribosome is its RNA.

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Mutual Arrangement of Ribosomal RNA and Proteins (Quaternary Structure)ted many years ago, extended regions of rRNA in the ribosome are exposed to the environment and are open to the action of various agents, such as nucleases. This fundamental difference compared to viral particles is understandable, since the ribosome is a functional structure in which RNA should act

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