Titlebook: Rheumatology in Questions; Haralampos M. Moutsopoulos,Evangelia Zampeli,Panay Book 20181st edition Springer International Publishing AG 20

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Autoimmune Rheumatic Disorders: Pathogenetic and Laboratory Aspectsuction of the affected organ (e.g., synovium in rheumatoid arthritis). The presence of leukocytosis and acute-phase proteins (C-reactive protein) characterizes the autoimmune disorders as inflammatory (e.g., vasculitis), while their absence as not inflammatory (e.g., systemic lupus erythematosus, SL

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STRIA

Inflammatory Muscle Disease-tRNA synthetases (anti-Jo1) for mechanic’s hands, arthritis, ILD, and RP; (f) anti-SRP (signal recognition particle), for severe muscle and heart involvement; (g) anti-HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase) for statin use-related necrotizing myopathy; (h) anti-MDA5 (melanoma differ

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Sj?gren’s Syndrome, IgG4-Related Disorders manifestations of SS. After excluding other causes of sicca symptomatology, patients should be assessed for lacrimal and salivary gland function (ocular staining with lissamine green or rose bengal, Schirmer’s test and unstimulated saliva secretion, respectively), and a biopsy of labial minor saliv

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Vasculitides and Related Diseasesangiitis (GPA, formerly known as Wegener’s granulomatosis), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA, formerly known as Churg-Strauss syndrome). Other non-ANCA-associated small-vessel vasculitides are typically characterized by either the presence of im

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Hiatal-Hernia

Rheumatic Disorders Associated with Metabolic, Endocrine, and Hematological Diseasesontractures, diabetic cheiroarthropathy, diffuse idiopathic skeletal hyperostosis, shoulder bursitis, and neuropathic arthropathy are some of the musculoskeletal manifestations associated with diabetes. In patients with hyperthyroidism, rheumatic manifestations include osteoporosis, painless proxima