Titlebook: Rheumatic Disease in Geriatrics; Diagnosis and Manage Gleb Slobodin,Yehuda Shoenfeld Book 2020 Springer Nature Switzerland AG 2020 Late ons

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Systemic Lupus Erythematosus in Geriatricstibodies to nuclear and cytoplasmic antigens. Although SLE is most prevalent among women of childbearing age, it may present at any age and in either gender. Clinical manifestations are similar at all ages but incidence and severity differ. Late onset SLE is defined as age of onset of 50 years and a

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Systemic Sclerosis in the Elderlyate onset SSc (LOSSc) is usually defined as an onset beyond 60?years of age. The most common presentation of LOSSc is limited disease, anti-centromere positive, with less digital ulcers (DU) than expected, but tendency to cardiac involvement including high rate of primary and mixed pulmonary hyperte

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Pharmacokinetics of Anti-Rheumatic Drugs in a Geriatric Patientht dose, safety etc. In this chapter we will?focus on the more common drugs used for rheumatic diseases, discuss specific pharmacokinteic and pharmacodynamic changes in the elderly that might influence these drugs safety and efficacy, and suggest?preferable choices of drug therapy in this population.?

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Biologic Drugs and Small Molecules for an Elderly Patient with the Rheumatic Diseaserticularly those aged 75?years or more. One of the strategies for choosing the right anti-rheumatic biologic drug for an elderly with multiple co-morbidities, in the era of multiple biologic medicines and small molecules with similar efficacy, can be based on patient’s background and the known safety profile of the therapeutics.

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Book 2020 of ageing on musculoskeletal and immune systems and specifies impact of a variety of inflammatory and degenerative rheumatic disorders on the elderly. The clinical diagnostic approach to an older individual with musculoskeletal complaints is a cornerstone of this book, which includes also insights

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Epigenetics of the Aging Musculoskeletal Systempects of epigenetic changes in aging. It further reviews the emerging involvement of impaired epigenetic regulation in age-related pathologies of muscles and bones. Particular emphasis is put on the latest discoveries in the field in order to acquaint the readers with cutting-edge research related to these topics.

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Vaccination of Geriatric Population with Rheumatic Conditionst effective strategies to prevent infection is vaccination. The accumulated data on the safety and effectiveness of vaccines warrant immunization with the majority of vaccines for patients with rheumatic diseases, especially vaccinations against influenza and pneumococci.

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Musculoskeletal Ultrasound in the Diagnosis of Rheumatic Disease in the Elderlysis of several common rheumatologic conditions in elderly patients including rheumatoid arthritis (RA), spondyloarthritis (SpA), polymyalgia rheumatica (PMR), giant cell arthritis (GCA), and crystal-induced arthropathies.