Titlebook: Reviews of Physiology, Biochemistry and Pharmacology, Vol. 171; Bernd Nilius,Pieter de Tombe,Ole H. Petersen Book 2016 The Editor(s) (if a

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978-3-319-82916-6The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

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Functional Impact of Ryanodine Receptor Oxidation on Intracellular Calcium Regulation in the Heart,remains incomplete. Several oxidative modifications, including .-glutathionylation and .-nitrosylation, have been suggested playing an important role in the regulation of RyR2 activity. Moreover, oxidative stress can increase RyR2 activity by forming disulfide bonds between two neighboring subunits

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Christine E. Genge,Eric Lin,Ling Lee,XiaoYe Sheng,Kaveh Rayani,Marvin Gunawan,Charles M. Stevens,Ali

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