Titlebook: Retinal Degenerative Diseases; Joe G. Hollyfield,Robert E. Anderson,Matthew M. La Conference proceedings 2006 The Editor(s) (if applicable

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Conference proceedings 2006ng in the field. THe topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration..

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A First Locus for Isolated Autosomal Recessive Optic Atrophy (ROA1) Maps to Chromosome 8q21-q22f DOA has been demonstrated. Three loci have been reported: OPA1 [3q28–q29; MIM 165500], OPA4 [18q12.2–q12.3; MIM 605293, and OPA5 (22q12.1–q13.1).. OPA1 which accounts for about 90% of DOA is due to mutations in the Msp1 protein [MIM 605290].

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