Titlebook: Retinal Degenerative Diseases; Mechanisms and Exper John D. Ash,Christian Grimm,Catherine Bowes Rickma Conference proceedings 2014 The Edit

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Cell Type-Specific Epigenetic Signatures Accompany Late Stages of Mouse Retina Developmentpoints during late mouse retina development. We merged these data with our previous retina developmental expression profiles and show that there are several epigenetic signatures specific for different functional groups of genes. The main conclusion from our study is that epigenetic signatures defin

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Programmed Cell Death During Retinal Development of the Mouse Eyehe neuronal progenitor population is affected. In the mouse eye, this kind of programmed cell death begins at around embryonic day (E) 12.5 and peaks between E14.5 and E16.5. The second phase of programmed cell death occurs during synaptogenesis within the first 2 postnatal weeks. Important signalin

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Spatial and Temporal Localization of Caveolin-1 Protein in the Developing Retinading uveitis, diabetic retinopathy, and primary open angle glaucoma. Genetic ablation of Cav-1 causes retinal functional deficits due to disruptions in environmental homeostasis. To better understand Cav-1 function in the retina, we examined its expression/localization during postnatal retinal devel

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AIPL1 Protein and its Indispensable Role in Cone Photoreceptor Function and Survivalse is due to requirement for AIPL1 in both rod and cone photoreceptor cell survival and function. . is expressed very early during retinal development in both rods and cones. In adult primates, robust expression of . is found in rods but not in cones. Mouse models revealed the importance of AIPL1 in

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