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Titlebook: Resistance to Anti-Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways; Yosef Yarden,Moshe Elkabets Book 2018

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發(fā)表于 2025-3-26 21:30:31 | 只看該作者
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發(fā)表于 2025-3-27 01:48:29 | 只看該作者
Resistance Mechanisms to Cyclin-Dependent Kinase Inhibitors, cycle deregulation is a hallmark of cancer, and CDKs have long been considered attractive targets for anti-cancer agents. After initial failures of pan-CDKi in clinical trials, two highly specific CDK4/6 inhibitors, palbociclib and ribociclib, are now FDA-approved in hormone receptor-positive breas
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發(fā)表于 2025-3-27 07:27:20 | 只看該作者
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發(fā)表于 2025-3-27 11:04:26 | 只看該作者
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發(fā)表于 2025-3-27 16:57:06 | 只看該作者
Mechanisms of Action and Resistance of Trastuzumab in Breast Cancer,wever, resistance to trastuzumab, either . or acquired resistance, presents a major clinical challenge. Here, we summarize the mechanisms of action and resistance of trastuzumab in breast cancer and discuss potential strategies to overcome resistance.
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發(fā)表于 2025-3-27 20:57:56 | 只看該作者
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發(fā)表于 2025-3-28 01:22:08 | 只看該作者
a geometric structure or a long-range interaction. The farther spin interactions than the nearest sites stem from a coupling with other degrees of freedom in many realistic materials. Among them, the spin-lattice interaction has a large contribution for the effective spin interaction, and the spin-P
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發(fā)表于 2025-3-28 03:36:23 | 只看該作者
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發(fā)表于 2025-3-28 09:34:11 | 只看該作者
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