Titlebook: Regulation of Phosphate and Mineral Metabolism; Shaul G. Massry,Joseph M. Letteri,Eberhard Ritz Book 1982 The Editor(s) (if applicable) an

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Protein Phosphorylation in Proximal Tubular Brush-Border MembranesMany processes of the living cell are currently believed to be finally regulated via the phosphorylation status of some of the proteins involved, whereby such phosphorylation processes can be influenced by various factors, e.g. cAMP and/or Ca.-ions (1).

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Abnormal Tubular Pi Adaptation to Dietary Pi Restriction and Decreased Calcium Reabsorption in X-LinThe renal transport of Pi is under a powerful parathyroid hormone-independent adaptation mechanism (1,2). It has been suggested (3) that this adaptation mechanism could be defective in X-linked hypophosphatemia, a disease characterized by vitamin D-resistant rickets and decreased tubular reabsorption of Pi (4).

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The Effects of Calcium on ADH Action in Cortical Collecting Tubules Perfused ,, (10 mM) have been shown to block ADH-induced water flow in the toad urinary bladder (1,2). To test the effects of smaller elevations of calcium level on ADH action in a mammalian system, studies were performed in the ADH responsive cortical collecting tubule, “l(fā)ight” segment (3).

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Regulation of Phosphate and Mineral Metabolism978-1-4684-4259-5Series ISSN 0065-2598 Series E-ISSN 2214-8019