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Titlebook: Randomised Controlled Clinical Trials; Christopher J. Bulpitt Book 1996Latest edition Springer Science+Business Media New York 1996 drugs.

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發(fā)表于 2025-3-21 18:27:21 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Randomised Controlled Clinical Trials
編輯Christopher J. Bulpitt
視頻videohttp://file.papertrans.cn/822/821114/821114.mp4
圖書封面Titlebook: Randomised Controlled Clinical Trials;  Christopher J. Bulpitt Book 1996Latest edition Springer Science+Business Media New York 1996 drugs.
描述After 13 years there are new areas to discuss and more recenttrials to be included. Good clinical practice; evaluation of qualityof life; measurement of the benefit:risk comparison; determination ofcost- effectiveness and cost utility; stopping rules for trials;meta-analysis and subgroup analysis are all new sections. Thereferences are expanded from 305 to 512 and include the recentadvances in trial design, such as the .n.-of-1 trials andmegatrials, and up-to-date examples to illustrate the points made inthe 20 chapters.
出版日期Book 1996Latest edition
關鍵詞drugs; evaluation
版次2
doihttps://doi.org/10.1007/978-1-4615-6347-1
isbn_softcover978-1-4613-7915-7
isbn_ebook978-1-4615-6347-1
copyrightSpringer Science+Business Media New York 1996
The information of publication is updating

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沙發(fā)
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Recruitment of Subjects,The recruitment of subjects must be considered very carefully to ensure that sufficient persons with the characteristics required by the investigators are enrolled within an appropriate period of time. The number of subjects is of great importance and was discussed in chapter 6.
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,The Conduct of the Trial — Good Clinical Practice,are foreseen and taken into account of prior to the start of the trial and those that are unexpected. Murphy’s law states, “..” This law has been attributed to captain E Murphy, a development engineer, who applied it first to an individual technician saying, “.” [215].
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Early Trials on New Drugs, three phases of early trials: trials to determine safety and early clinical pharmacology (phase I); trials to determine clinical efficacy and further clinical pharmacology (phase II); and trials for the early clinical development of the drug (phase III). A drug regulatory authority may be involved in these early trials.
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asurement of the benefit:risk comparison; determination ofcost- effectiveness and cost utility; stopping rules for trials;meta-analysis and subgroup analysis are all new sections. Thereferences are expanded from 305 to 512 and include the recentadvances in trial design, such as the .n.-of-1 trials a
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