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Titlebook: Proteases: Structure and Function; Klaudia Brix,Walter St?cker Book 2013 Springer-Verlag Wien 2013 enzyme.proteinase.proteinase function.p

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書(shū)目名稱(chēng)Proteases: Structure and Function
編輯Klaudia Brix,Walter St?cker
視頻videohttp://file.papertrans.cn/762/761559/761559.mp4
概述Written by designated experts in the field defined models are described.Ensures a better understanding of biological significance of proteinases.Clearly shows the diversity and networking of enzymes.I
圖書(shū)封面Titlebook: Proteases: Structure and Function;  Klaudia Brix,Walter St?cker Book 2013 Springer-Verlag Wien 2013 enzyme.proteinase.proteinase function.p
描述Proteolysis is an irreversible posttranslational modification affecting each and every protein from its biosynthesis to its degradation. Limited proteolysis regulates targeting and activity throughout the lifetime of proteins. Balancing proteolysis is therefore crucial for physiological homeostasis. Control mechanisms include proteolytic maturation of zymogens resulting in active proteases and the shut down of proteolysis by counteracting endogenous protease inhibitors. Beyond the protein level, proteolytic enzymes are involved in key decisions during development that determine life and death – from single cells to adult individuals. In particular, we are becoming aware of the subtle role that proteases play in signaling events within proteolysis networks, in which the enzymes act synergistically and form alliances in a web-like fashion. Proteases come in different flavors. At least five families of mechanistically distinct enzymes and even more inhibitor families are known to date, many family members are still to be studied in detail. We have learned a lot about the diversity of the about 600 proteases in the human genome and begin to understand their physiological roles in the d
出版日期Book 2013
關(guān)鍵詞enzyme; proteinase; proteinase function; proteinase structure; Protein Structure
版次1
doihttps://doi.org/10.1007/978-3-7091-0885-7
isbn_softcover978-3-7091-1939-6
isbn_ebook978-3-7091-0885-7
copyrightSpringer-Verlag Wien 2013
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