| 書目名稱 | Platelet-Activating Factor and Related Lipid Mediators | | 編輯 | Fred Snyder | | 視頻video | http://file.papertrans.cn/750/749307/749307.mp4 | | 圖書封面 |  | | 描述 | Platelet-activating factor (PAF) is the commonly used name for a group of potent biologically active, ether-linked phospholipids, the alkylacetylglycerophospho- cholines. Following the identification of the chemical structure of P AF in 1979, much progress has been made in our understanding of these phospholipid medi- ators. This is particularly true from the points of view of their molecular structural requirements for expression of biological activity, their biosynthesis and cata- bolism, their diverse range of biological activities, evidence for their specific recep- tors at the cell surface, the development of specific antagonists for use in receptor studies and for testing as potential anti-PAF drugs, and implications about their involvement in health and disease. Chapters in this book cover the current status of these general areas of PAF research. Although an enormous amount of information has been published about this interesting new type of phospholipid mediators, questions about their mechanism of action, regulatory controls, and the precise role and relative importance of P AF in specific diseases and physiological functions remain to be answered. Since the 1979 discover | | 出版日期 | Book 1987 | | 關(guān)鍵詞 | Lipid; Mammalia; development; enzymes; metabolism; tissue | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4684-5284-6 | | isbn_softcover | 978-1-4684-5286-0 | | isbn_ebook | 978-1-4684-5284-6 | | copyright | Plenum Press, New York 1987 |
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