Titlebook: Organic Cation Transporters in the Central Nervous System; Lynette C. Daws Book 2021 The Editor(s) (if applicable) and The Author(s), unde

要旨

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書(shū)目名稱(chēng)Organic Cation Transporters in the Central Nervous System讀者反饋




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廣口瓶

Organic Cation Transporters in the Central Nervous System978-3-030-82984-1Series ISSN 0171-2004 Series E-ISSN 1865-0325

Arb853

Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/o/image/703783.jpg

JADED

https://doi.org/10.1007/978-3-030-82984-1organic cation transporter (OCT); plasma membrane monoamine transporter (PMAT); monoamine homeostasis;

辭職

Lynette C. DawsFirst book that comprehensively synthesizes literature pertaining to the role of OCTs and PMAT in the CNS.Lays emphasis on health, disease and therapeutics.Highlights the important role for OCTs and P

滲入

outskirts

Organic Cation Transporter Expression and Function in the CNS,. In particular, transporters belonging to the Solute Carrier (SLC) superfamily are emerging as major contributors, including the SLC22 organic cation/anion/zwitterion family of transporters (includes OCT1–3 and OCTN1–3), the SLC29 facilitative nucleoside family of transporters (includes PMAT), and

Indelible

Experimental Methods for Investigating Uptake 2 Processes In Vivo,ve yielded important information about Uptake 2 mechanisms in vivo. The techniques (scintillation microspectrophotometry, microdialysis, chronoamperometry, and voltammetry) are described in detail, and pivotal studies associated with each method are highlighted. It is clear from these reviewed works

Adjourn

Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implicationine transport have indicated the contribution of organic cation transporter 3 (OCT3) and plasma membrane monoamine transporter (PMAT) in histamine uptake, although the importance of these transporters in in vivo histamine clearance remains unknown. Immunohistochemical analyses have revealed the expr

無(wú)目標(biāo)

Organic Cation Transporters in Brain Catecholamine Homeostasis, are expressed widely throughout the brain. In contrast to DAT and NET, these transporters have higher capacity and lower affinity for catecholamines and are multi-specific, each with the capacity to transport all catecholamines. The expression of these transporters in the brain suggests that they p