Titlebook: Nanomedicines for Effective Cancer Therapy; Hitoshi Kasai,Hiroshi Uji-i,Johan Hofkens Book 2024 The Editor(s) (if applicable) and The Auth

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Targeted Drug Delivery for Cancer Therapy Using Functionalized Nanocarrierse therapies are based on passive accumulation in tumor tissues via enhanced permeability of tumor vasculature, namely the enhanced permeability and retention effect (EPR effect). However, the efficacy of EPR-based drug delivery is controversial because liposomal doxorubicin potentially has an insuf

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Cancer Photo Therapies that Target Mitochondriapeutic molecule of choice to act where it is needed and for the required time. Cancer photo therapy typically involves photochemical reactions induced by light irradiation to cause cell death. Over the past few decades, mitochondria have attracted considerable attention in the field of therapy. The

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Cell Membrane Mimetic Amphiphilic Phospholipid Polymers for Advanced Nanomedicinee, we introduce phospholipid polymers, whose molecular design is based on the surface structure of cell membranes, and their role in drug formulation. These phospholipid polymers are amphiphilic, can substantially enhance the solubility of drugs in aqueous media, and can permeate membranes through m

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3D Tumor Models—Nanomedicine in the Third Dimensionnced efficacy and reduced side effects has marked a significant step forward in cancer research. However, the promising results observed in preclinical studies show low translatability into the clinic, due to a lack of adequate preclinical models that faithfully mimic the complex tumor microenvironm

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