Titlebook: Notch Signaling; Immunity and Cancer Koji Yasutomo Book 2017 Springer Nature Singapore Pte Ltd. 2017 Notch.T cells.lymphoma.leukemia.tumori

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Notch Controls the Differentiation and Function of Cytotoxic CD8 T Cellsives a license to CD8 T cells to fully activate and become effector cells during priming. In this review, we discuss the recent progresses in the study of the regulation of the activation and function of CD8 T cells by Notch signaling.

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NOTCH in Malignant Lymphomaveloping thymocytes. The discovery of frequent . mutations in several mature B-cell malignancies, however, reminds us of the importance of NOTCH signaling in mature B cells, by means of reverse genetics.

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https://doi.org/10.1007/978-981-10-4971-2Notch; T cells; lymphoma; leukemia; tumorigenesis; cancer stem cells

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978-981-13-5280-5Springer Nature Singapore Pte Ltd. 2017

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The Two Faces of Notch in Solid Cancersnt and progression of cancer is an area of considerable interest, and a deeper knowledge of its influence on cellular processes will potentially lead to improvements in both the prevention and treatment of cancer.

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Koji YasutomoCovers all areas of Notch functions in immune cells and tumorigenesis.Provides coverage of controversial issues, further facilitating research in this field.Includes detailed descriptions of the relat

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