Titlebook: Neurotrophic Factors; Gary R. Lewin,Bruce D. Carter Book 2014 Springer-Verlag Berlin Heidelberg 2014 2014 BDNF.NGF.NT3.P75NTR.TrkA.pain.si

cancer

Engulf

The Biological Functions and Signaling Mechanisms of the p75 Neurotrophin Receptoream of these interactions are further modulated through regulated intramembrane proteolysis (RIP) of p75. and by interactions with numerous cytosolic partners. In this chapter, we discuss the intricate signaling mechanisms of p75., emphasizing how these signals are differentially regulated to mediate these diverse cellular functions.

委托

falsehood

熱烈的歡迎

voluble

Neurotrophins: Transcription and Translationi into neuronal plasticity of physiologically relevant brain regions. Here we review the transcriptional and translational mechanisms that control neurotrophin expression with a particular focus on the activity-dependent regulation of BDNF.

苦澀

Trk Receptors the full-length receptors will be described, as well as the biological functions of their truncated isoforms. Finally, the role of Trk receptors in the nervous system in health and disease will be discussed.

類型

Neurotrophin Signalling and Transcription Programmes Interactions in the Development of Somatosensoronal sub-type specification. This chapter explores the mechanisms by which this crosstalk between neurotrophin signalling and transcription programmes generates the diverse functional sub-types of somatosensory neurons found in the mature animal.

Retrieval

Obligatory