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Titlebook: Neurotoxin Modeling of Brain Disorders — Life-long Outcomes in Behavioral Teratology; Richard M. Kostrzewa,Trevor Archer Book 2016 Springe

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Perinatal 192 IgG-Saporin as Neuroteratogen,tical mantle, amygdala, and olfactory bulb. Perinatal immunotoxic lesions by 192 IgG-saporin induce long-lasting cholinergic depletion mimicking a number of developmental disorders reported in humans. The perinatal injection of 192 IgG-saporin induces several brain modifications, which are observed
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發(fā)表于 2025-3-27 20:15:06 | 只看該作者
NGF in Early Embryogenesis, Differentiation, and Pathology in the Nervous and Immune Systems,NGF, its precursor molecule pro-NGF, and their different receptor systems (i.e., TrkA, p75NTR, and sortilin) have key roles in the development and adult physiology of both the nervous and immune systems. Although the NGF receptor system and the pathways activated are similar for all types of cells s
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發(fā)表于 2025-3-28 01:22:36 | 只看該作者
Disrupted Circadian Rhythm as a Common Player in Developmental Models of Neuropsychiatric Disorders environment has reached far more clinical relevance given its potential influence on shaping brain function and thus mental health. Gestational stress and/or maternal infection during pregnancy has been related with an increased incidence of neuropsychiatric disorders, including depression and schi
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,The Use of Perinatal 6-Hydroxydopamine to Produce a Rodent Model of Lesch–Nyhan Disease,treatment. While it is known that the disease is intimately associated with dysfunction of the hypoxanthine phosphoribosyltransferase 1 (HPRT1) gene that codes for an enzyme of purine metabolism (hypoxanthine-guanine phosphoribosyltransferase) and is associated with neurological, behavioral, as well
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