Titlebook: Neuropathology Review; Richard A. Prayson Book 20011st edition Humana Press 2001 histology.muscle.neuropathology.pathology.trauma.tumor

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Richard A. Prayson MDchain bases generated through the actions of sphingosine kinase may be dephosphorylated by lipid phosphatases or cleaved at the C. carbon-carbon bond by the pyridoxal 5’-phosphate-dependent enzyme, sphingosine-1-phosphate lyase. By regulating intracellular levels of phosphorylated long chain bases,

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Richard A. Prayson MDecies (ROS) and c-jun-N-terminal kinase (JNK), and anti-apoptotic signals such as phosphatidylinositides (PI)-3 kinase and protein kinase C are inhibited by ceramide. Sphingosine-1-phosphate (S1P) competes with ceramide-induced cell death by blocking its generation and downstream pathways. This bala

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ions for eukaryotic cells. Sphingolipid metabolism pathways can utilize sugar, protein, nucleic acid, and other metabolites participating lipid transport in the circulation, play an essential role in maintaining cell homeostasis and are related to a variety of different diseases including lysosomal

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Book 20011st editionrview of the subject -the essential element of the neuropathology curriculum. Topics range from basic information on the spectrum of neurologic-related disease to pertinent pictorial examples of many neuropathologic conditions. For each topic there are self-assessment tests based on both textual and

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ding. Concise yet comprehensive, Neuropathology Review provides an effective and easy-to-use refresher course for those working pathologists wishing to update their skills, as well as for those preparing to take board exams in neuropathology.978-1-59259-133-6

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