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Titlebook: Neuroblastoma; Discoveries and Chal Shahab Asgharzadeh,Frank Westermann Book 2024 Springer Nature Switzerland AG 2024 Sympathetic nervous s

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發(fā)表于 2025-3-21 16:03:34 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)Neuroblastoma
副標(biāo)題Discoveries and Chal
編輯Shahab Asgharzadeh,Frank Westermann
視頻videohttp://file.papertrans.cn/664/663927/663927.mp4
概述Provides a synopsis of current clinical and basic research on neuroblastoma.Presents the state of the art regarding tumor microenvironment and targeted therapeutics such as immunotherapy.Edited and au
叢書(shū)名稱(chēng)Pediatric Oncology
圖書(shū)封面Titlebook: Neuroblastoma; Discoveries and Chal Shahab Asgharzadeh,Frank Westermann Book 2024 Springer Nature Switzerland AG 2024 Sympathetic nervous s
描述.This book provides a state-of-the-art review of the biology, treatment, and other critical aspects of neuroblastoma, reflecting the dramatic advances that have been achieved in understanding and management. Topics are arranged according to the book’s dominant themes of the “seed” (tumor genomics, epigenetics, metabolism, and stem cells) and the “soil” (tumor microenvironment, adaptive and innate immunity, and exosomes) and how both of these influences can serve as rich targets for intervention, whether by targeted molecular therapy or immunotherapy. Therapeutic strategies that are currently in use or under consideration for the future are discussed in detail, with the focus on precision medicine. Further individual chapters are devoted to the biology and genetics of relapsed/refractory neuroblastoma and emerging methods of evaluating tumor burden. Finally, in keeping with the, albeit modest, increase in cure rates in high-risk disease,?immune and cellular therapies?are reviewed. This coverage of what is becoming a not-so-enigmatic tumor will appeal to a broad readership including both experimental oncologists and clinicians who care for patients with neuroblastoma..
出版日期Book 2024
關(guān)鍵詞Sympathetic nervous system tumors; Childhood tumor genomics and epigenetics; Pediatric precision medic
版次1
doihttps://doi.org/10.1007/978-3-031-51292-6
isbn_softcover978-3-031-51294-0
isbn_ebook978-3-031-51292-6Series ISSN 1613-5318 Series E-ISSN 2191-0812
issn_series 1613-5318
copyrightSpringer Nature Switzerland AG 2024
The information of publication is updating

書(shū)目名稱(chēng)Neuroblastoma影響因子(影響力)




書(shū)目名稱(chēng)Neuroblastoma影響因子(影響力)學(xué)科排名




書(shū)目名稱(chēng)Neuroblastoma網(wǎng)絡(luò)公開(kāi)度




書(shū)目名稱(chēng)Neuroblastoma網(wǎng)絡(luò)公開(kāi)度學(xué)科排名




書(shū)目名稱(chēng)Neuroblastoma被引頻次




書(shū)目名稱(chēng)Neuroblastoma被引頻次學(xué)科排名




書(shū)目名稱(chēng)Neuroblastoma年度引用




書(shū)目名稱(chēng)Neuroblastoma年度引用學(xué)科排名




書(shū)目名稱(chēng)Neuroblastoma讀者反饋




書(shū)目名稱(chēng)Neuroblastoma讀者反饋學(xué)科排名




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Genetic Predisposition,ity and also tumor aggressiveness. More recently, sequencing studies of germline DNA obtained from children diagnosed with neuroblastoma have revealed rare variants in known cancer predisposition genes that may contribute to neuroblastoma susceptibility and are predicted to have larger effect size.
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The Genetic Basis of the Divergent Clinical Courses in Neuroblastoma,st, such alterations are invariably lacking in low-risk neuroblastoma, suggesting that absence of telomere maintenance and consecutive lack of cellular immortality may cause spontaneous regression and differentiation. In addition, oncogenic mutations have been found in the gene ., encoding for a rec
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