Titlebook: Molecular Determinants of Radiation Response; Theodore L. DeWeese,Marikki Laiho Book 2011 Springer Science+Business Media, LLC 2011 EGFR S

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Immune Stimulation by Oligonucleotides,d DNA backbones can cause immune activation which is concentration-and length-dependent and sequence-independent. However, the different backbones currently under development for antisense applications differ greatly in the degree to which they induce immune effects. As might be expected, neutral ba

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Toxic and Metabolic Disorders,ell as of modern neuroimaging. Attention is paid here to disorders that have typical MR features, and to rare disorders, the cases of which are our own, and were observed and verified clinically by laboratory tests and stereotactic biopsy.

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Physical Exercise Can Spur Beneficial Neoangiogenesis and Microvasculature Remodeling Within the Healar signaling pathways how exercise could affect neoangiogenesis and ameliorate performance of the heart. Key roles in this process are mechanical forces (mainly increased velocity of blood flow and shear stress) and subsequent rise of angiogenic biological factors (mainly VEGFA).

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Protocols for the Study of Taxanes Chemosensitivity in Prostate Cancer,mitosis and the subsequent induction of the intrinsic apoptotic pathway. Since taxanes are widely used for the treatment of advanced prostate cancers, we present in this chapter protocols that allow the study of the prostate cancer sensitivity as well as determine the mechanisms of resistance to these chemotherapeutic agents.

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Polyhedral Regions and Polynomials,ovement patterns. It examines the root causes and nature of the conflict between farmers and herders and assesses its effect on the state, society and the economy, with a view to offering sustainable recommendations for its resolution.