Titlebook: Manual of Antisense Methodology; Gunther Hartmann,Stefan Endres Book 1999 Springer Science+Business Media New York 1999 Nucleotide.cell cu

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Finbarr E Cotter,Dean Fennellsic and painting have for a long time been sources of new developments in mathematics, and vice versa. Many great painters have seen no contradiction between artistic and mathematical endeavors, contributing to the progress of both, using mathematical principles to guide their visual creativity, enr

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How to Exclude Immunostimmulatory and Other Nonantisense Effects of Antisense Oligonucleotides. However, like other polyanionic molecules, oligonucleotides have been found to have a variety of biologic activities that are independent of an antisense mechanism of action. These nonantisense activities, which can confound experimental interpretation, may be avoided through understanding the seq

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Inhibition of TNF Synthesis by Antisense Oligonucleotideslammatory and immune responses (Beutler et al., 1989). TNF-α is produced by a number of cell types including monocytes/ macrophages, mast cells, lymphocytes, and keratinocytes. TNF-β is produced primarily by activated lymphocytes. TNF is released early in the inflammatory cascade and triggers a wide

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