Titlebook: Lipid Signaling in Human Diseases; Julian Gomez-Cambronero,Michael A. Frohman Book 2020 Springer Nature Switzerland AG 2020 Lipid signalin

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Vanina Zaremberg,Suriakarthiga Ganesan,Mark Mahadeodes Zentrums für europ?ische Wirtschaftsforschung (ZEW) rund 60 % aller deutschen Haushalte Anteile an Investmentfonds. Dabei sind aus wirtschaftlicher Sicht an einer solchen Investmentanlage sowohl die Anleger als Investoren, die Verwahrstelle, welche den Investmentfonds verwaltet, sowie die Kapita

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des Zentrums für europ?ische Wirtschaftsforschung (ZEW) rund 60 % aller deutschen Haushalte Anteile an Investmentfonds. Dabei sind aus wirtschaftlicher Sicht an einer solchen Investmentanlage sowohl die Anleger als Investoren, die Verwahrstelle, welche den Investmentfonds verwaltet, sowie die Kapita

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Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinomadwide. Thus, there is a need to find biomarkers of early HCC as well as the development of more effective treatments for the disease. Sphingosine-1-phosphate (S1P) is a pleiotropic lipid signaling molecule produced by two isoforms of sphingosine kinase (SphK1 and SphK2) that is involved in regulatio

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Sphingosine Kinases as Druggable Targetse, are involved in pathophysiological processes. In this chapter, we appraise the evidence that both enzymes are druggable and describe how isoform-specific inhibitors can be developed based on the plasticity of the sphingosine-binding site. This is contextualised with the effect of sphingosine kina

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Prospects for PLD Inhibition in Cancer and Thrombotic Diseasecal and animal disease models for two decades. PLD1 and PLD2, which are activated as a consequence of extracellular signaling events and generate the second messenger signaling lipid phosphatidic acid (PA), have been reported to play roles in settings ranging from platelet activation to the response

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