Titlebook: Investigations of Cellular and Molecular Biophysical Properties by Atomic Force Microscopy Nanorobot; Mi Li Book 2018 Springer Nature Sing

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Introduction to Atomic Force Microscopy-Based Nanorobotics for Biomedical Applications,logy with unprecedented opportunities. Atomic force microscopy (AFM)-based nanorobotics is capable of detecting multiple physical properties of single cells and single molecules in their native states, considerably complementing traditional biochemical assays. The unique information obtained by AFM

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Measuring the Mechanical Properties of Single Cells by AFM,nted. Then spherical probes were fabricated by gluing individual spheres to the AFM probe based on optical-guided AFM micromanipulations. With the use of spherical probes, the Young‘s modulus of human erythrocytes and three types of human suspended cancerous cells with different invasiveness was mea

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Mapping Membrane Proteins on Cell Surface by AFM,of biotin-linked tips (rituximab-linked tips), avidins coated on the surface of mica (CD20s on the surface of lymphoma Raji cell) were exactly recognized from the adhesion images obtained by PFT imaging, and the specificity of molecular interactions was confirmed by control experiments.