Titlebook: International Conference on Advanced Intelligent Systems for Sustainable Development (AI2SD’2023); Advanced Intelligent Mostafa Ezziyyani,J

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Oumaima Manchadi,Fatima-Ezzahraa Ben-BOUAZZA,Zineb El Otmani Dehbi,Zakaria Said,Bassma Jioudiloped and investigated for the improved delivery?of drugs?to the brain disorders. The effective delivery and penetration across the endothelial cells of brain can be achieved by considering various physiochemical factors of nanoparticles and of drugs while designing and formulation development. Addi

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Zahra Mohammad Alipoor,Hosna Salmanin developed. These will depict enhanced therapeutic efficacy with reduced doses and aid in efficient BBB crossing of the drugs with minimum side effects. This chapter explains the pathophysiological mechanism involved in developing PD, conventional drug-delivery methods, and their challenges. Advanc

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Zineb El Otmani Dehbi,Fatima-Ezzahraa Ben-Bouazza,Oumaima Manchadi,Mohamed Karra,Wajih Rhalem,Lahceno bypass the blood–brain barrier to reach the central nervous system. The presented chapter highlights the method of intranasal delivery in mice using chitosan–siRNA nanoparticle formulation, under mild anesthesia and the identification of successful siRNA delivery in the brain tissues, through hist

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Sofia Sehli,Zainab El Ouafi,Casey Eddington,Soumaya Jbara,Kasambula Arthur Shem,Islam El Jaddaoui,Ayo bypass the blood–brain barrier to reach the central nervous system. The presented chapter highlights the method of intranasal delivery in mice using chitosan–siRNA nanoparticle formulation, under mild anesthesia and the identification of successful siRNA delivery in the brain tissues, through hist

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