| 書目名稱 | Integrative Structural Biology with Hybrid Methods | | 編輯 | Haruki Nakamura,Gerard Kleywegt,John L. Markley | | 視頻video | http://file.papertrans.cn/469/468994/468994.mp4 | | 概述 | Presents impact of the integrative structural biology.Provides Future perspective of the hybrid methods and their applications.Covers detailed description of experimental and computational methods in | | 叢書名稱 | Advances in Experimental Medicine and Biology | | 圖書封面 |  | | 描述 | .This book presents?a new?emerging?concept of "Integrative Structural Biology". It covers?current trends of the molecular and cellular structural biology,?providing new methods to observe, validate, and keep the structural models of the large cellular machines with recent scientific results. Structures of very large macromolecular machines in cells are being determined by combining observations from complementary experimental methods. Thus, this volume presents the each methods such as X-ray crystallography, NMR spectroscopy, 3DEM, small-angle scattering (SAS), FRET, crosslinking, and enables the readers to understand?the hybrid methods. This book?discusses how those integrative models should be represented, validated and archived. A unique highlight of this book is discussion of?the data validation and archive, which are big problems in this filed along with the progress of this field. The?researchers?in biology will be interested inthis book as a guide book for learning the current structure biology, but also those in?structure biology?may use this book as a comprehensive reference to cover broad topics.. | | 出版日期 | Book 2018 | | 關(guān)鍵詞 | Hybrid/integrative methods; structural biology; PDB; EMDB; SASBDB; PMP; Protein Structure | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-13-2200-6 | | isbn_ebook | 978-981-13-2200-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | Springer Nature Singapore Pte Ltd. 2018 |
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