Titlebook: Inotropic Stimulation and Myocardial Energetics; Hj. Just,Ch. Holubarsch,H. Scholz Conference proceedings 1989 Springer-Verlag Berlin Heid

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On the mechanism of positive inotropic effects of alpha-adrenoceptor agoniststhy hearts. The reduced beta-adrenergic effects can in part be explained by an increased content of signal transducing G.-proteins. It is tempting to investigate whether other G proteins are also altered in severe congestive heart failure.

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Modulation of the autonomic control of the failing heartuse cardiac output is increased with a more normal combination of heart rate, stroke volume, and filling pressure. The beneficial effects of xamoterol are discussed as being especially important for failing ischemic hearts, because the balance between energy supply and energy demand may be improved by xamoterol.

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ailure have recently met with considerable criticism and reevaluation. It is generally agreed that unloading of the heart, either through vasodilation and/or diuresis, improves the working conditions of the dilated, failing heart. It reduces myocar- dial oxygen consumption through reduction of chamb

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Impacts of COVID-19 on Hotels and Lodges in Tourism Destination Areas in Bulawayo, Zimbabwental to the accommodation tourism sectors in times of crisis. While this study focused on Bulawayo province, future research can be replicated in other cities and provinces in the nation. The use of mixed methods to investigate the impacts of COVID-19 on the tourism sector can also bring out insight