Titlebook: Innovations in Molecular Mechanisms and Tissue Engineering; Jeanne Wilson-Rawls,Kenro Kusumi Book 2016 Springer International Publishing S

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IDEAS

Regeneration: Lessons from the Lizard, including humans, have very limited capacity. The combination of cellular and tissue-based studies together with high throughput sequencing technologies now permit investigations into the molecular mechanisms underlying regeneration of appendages in vertebrates. As the first squamate reptile with a

CARE

Dependency on Non-myogenic Cells for Regeneration of Skeletal Muscle,and fish, entire muscles can be regenerated in response to amputation. Understanding the underlying mechanisms that control these processes has therapeutic implications for individuals where the severe loss of muscle or chronic destabilization has led to the histopathological accumulation of fibroti

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DRILL

Digit Regeneration in Mammals,urodele limb responds to amputation via a process called epimorphic regeneration, and involves the formation of a blastema comprised of proliferating cells that are undifferentiated. The regeneration process involves a series of stages (e.g. inflammation, wound closure, dedifferentiation, cell migra

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trigger

Regenerative Strategies for the Central Nervous System,nts fall short of directly addressing the disease/injury pathology that blocks neuroregeneration to restore full functional recovery. However, recent advances in neural tissue engineering and regenerative medicine provide new avenues and approaches to tackling multi-faceted disease/injury pathology.

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