Titlebook: In Vivo Immunology; Histophysiology of t Paul Nieuwenhuis,A. A. Broek,M. G. Hanna Book 1982 The Editor(s) (if applicable) and The Author(s)

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Antigens Associated with Bursal and Thymic Reticular Epithelial Cells that chicken thymic and bursal reticular epithelial (REp) cells are able to induce in vitro the appearance of T and B lymphocyte surface markers, respectively, on embryonic precursor cells. In addition, bursa-derived factor(s) have been shown to influence B cell development (4,5). Chicken thymus RE

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The Development of B Lymphocytes and Their Reactivity in Pig Fetusesaru (1). In the pig, as in other animal species, there are two distinct pathways of lymphoid cell differentiation leading to generation of B and T lymphocytes (2,3). First, lymphocytes which express markers of T-cell lineage (receptors for SRBC and binding sites for anti-pig T serum) appear in thymu

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Distribution and Functional Properties of PNA+ and PNA- Cells in Central and Peripheral Lymphoid Orgition, more recent studies revealed that PNA may preferentially bind to cells acting as suppressors. PNA+ suppressor cells were detected in the fetal liver (3) and aging mouse spleen (4), as well as in the thymus of young adult animals (5). Furthermore, antigen-specific suppressors in the adult sple

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Functional Studies on Subpopulations of B-Lymphocytes and Bone Marrow Cellsential stem cell in the bone marrow. The T-cell lineage has been extensively studied using the surface markers available (1,2). Although a number of studies do suggest the existence of subpopulations of B-cells, a system of functional markers analogous to the Lyt system of T-cells has not yet been d

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Marginal Zones: The Largest B Cell Compartment of the Rat Spleen large numbers of intermediate sized lymphocytes. In this report we summarize the characteristics of these cells and compare them with the lymphocytes found in the inner small lymphocytic zones of the splenic white pulp.

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The Proliferative Activity of Antibody Forming Cells in the Mouse Bone Marrowr DNP-Ficoll. Peak proliferative activity was found during the first few days of the response. Elimination of the proliferating cells in this period caused a profound and long-lasting suppression of the antibody formation in the marrow.

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The Origin of Marginal-Zone Cells,2). Surface marker analyses (3–6) have provided strong evidence that these cells are B lymphocytes. Also marginal zone lymphocytes are absent from the spleens of rats treated with heterologous anti-μ antibody from birth (6). In rat spleens marginal-zone B cells outnumber the B lymphocytes found in