Titlebook: Immunotherapy and Biomarkers in Neurodegenerative Disorders; Martin Ingelsson,Lars Lannfelt Book 2016 Springer Science+Business Media New

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1557-2153 he-art contributions from renowned experts.Features practica.This practical volume examines a number of topicsthat explore the current status of immunotherapy and diagnostic markers forneurodegenerative disorders. With a focus on Alzheimer’s disease, the firstsections of the book examine immunothera

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Active Immunization Against the Amyloid-β Peptidegeting amyloid-β, specifically Aβ., as this protein is thought to initiate the cascade of events that lead to the disease. This chapter focuses on active immunotherapy (vaccines) and specifically on therapies that currently are in clinical development.

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Alpha-Synuclein as a Diagnostic Biomarker for Parkinson’s Disease shown promising results, but further studies are needed to prove their diagnostic usefulness. In addition to analyses of body fluids, detection of α-synuclein in peripheral tissues—such as subcolonic mucosa and parotid gland—seem to offer novel interesting diagnostic possibilities.

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Kiran Yanamandra,Marc I. Diamond,David M. Holtzman

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Joakim Bergstr?m,Martin Ingelsson M.D., Ph.D.ion frequently has not been confirmed by sensitive and specific laboratory tests. The goal of this chapter is to review and update earlier surveys (e.g., Strauss and Davis 1973; Jaffe 1978; Davis and Johnsson 1983; Schuknecht and Donovan 1986; Davis 1990, 1993) of the role of viruses in development

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