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Titlebook: Immunology of the Skin; Basic and Clinical S Kenji Kabashima Book 2016 Springer Japan KK 2016 Skin immunology.Barrier functions.Allergies.S

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Keratinocytesstantly exposed to external pathogens, and keratinocytes are the first line of defense against invading pathogens. Keratinocytes sense pathogens through innate immune receptors and produce various cytokines, chemokines, and antimicrobial proteins, which have antimicrobial activity against diverse pa
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γδ T Cellspithelial tissues including the skin, especially in mice. In contrast to conventional αβ T cells with the diverse T-cell receptor (TCR) repertoire for adaptive immunity, epithelial γδ T cells express tissue-specific invariant or restricted TCRs and have innate-like properties. Dendritic epidermal T
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Neutrophils and damage repair. Neutrophils are exquisitely sensitive to migratory stimuli, which enables them to rapidly home into injured tissues, including the skin, where they exert their effector functions. The latter include the release of preformed mediators from granules, production of reactive oxygen s
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