Titlebook: Immunological Mechanisms and Therapies in Brain Injuries and Stroke; Jun Chen,Xiaoming Hu,John H. Zhang Book 2014 Springer Science+Busines

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Small-Intestine

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Inflammation After Acute Brain Injuries Affects the Developing Brain Differently than the Adult Bra discuss the maturation-dependent contribution of glial and peripheral immune cells, differences in the blood–brain barrier structure and function in relation to injury, as well as the effect of immaturity on the function of several receptors on microglia/macrophages related to innate and acquired i

Working-Memory

Systemic Immune Responses after Experimental Stroke,optosis and consequent immunosuppression. In this chapter, we review key immunological aspects of stroke induction and immunosuppression in the context of an emerging concept called “brain–spleen injury cycling.” Moreover, we discuss the contribution to stroke severity of immune cells, including T a

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Infectious Burden and Risk of Stroke,ated, synergistically act to elevate risk of acute cerebral ischemic events. Infectious exposures are atypical cardiovascular risk factors requiring methodological and paradigmatic departures from traditional risk factor investigation approaches. Several parameters of pathogen activity have been mec

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Brain-Imaging

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Inflammation as a Therapeutic Target after Subarachnoid Hemorrhage: Advances and Challenges,e (ICP), reduced cerebral perfusion pressure (CPP), and decreased cerebral blood flow (CBF). The resultant hypoxic state alters autoregulation, ionic homeostasis, and excitotoxicity as well as initiates secondary injuries such as cytotoxic edema, blood-brain barrier (BBB) disruption, inflammation, a

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Minocycline, A Tetracycline Derivative, as a Potential Protective Agent for Acute Stroke,ed to provide neuroprotection in global brain ischemia in 1998. Since then these compounds, especially minocycline has been widely studied in numerous in vivo and in vitro models of chronic and acute brain diseases. While the exact mechanism of minocycline’s neuroprotective effect is not clear, mino