Titlebook: Hypoxia in Cancer: Significance and Impact on Cancer Therapy; Sukhes Mukherjee,Jagat Rakesh Kanwar Book 2023 The Editor(s) (if applicable)

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MicroRNA Signatures of Tumor Hypoxia,expression of miRNAs in different types of tumors in response to hypoxic conditions. The hypoxic microenvironment favors the selection of cancer stem-like cells that show features like indefinite self-renewal, chromosomal abnormalities, highly dysregulated differentiation, and tumor development. The

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piRNA-Based Cancer Therapy in Hypoxic Tumor,hows that additional factors may affect how the tumors react to hypoxia. Hypoxia is frequently found in solid tumors and is known to influence aggressive tumor activity, chemotherapy resistance, and radiation resistance, all of which lead to a bad prognosis for the cancer patient. PIWI-interacting R

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Hypoxia and the Metastatic Cascade,p process with several intercellular interactions. In this process, a metastatic cell overcomes many barriers and adapts to the changing microenvironment. Our understanding of motility, invasion and epithelial to mesenchymal transition has led to the identification of targetable signalling networks

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CRISPR/Cas9-Editing-Based Modeling of Tumor Hypoxia, exhibit tumor hypoxia, primarily caused by an insufficient and diverse vascular network. Hypoxia, brought on by inadequate blood flow and oxygen supply in tumors, reduces the sensitivity of tumor cells to anticancer therapy. The major cellular stressor, hypoxia, influences various molecular pathway

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Tumor-on-a-Chip: Microfluidic Models of Hypoxic Tumor Microenvironment,apy, one requires a superior cognizance of the tumor microenvironment (TME) including more sophisticated means to screen potential anticancer therapies. Hypoxia or low blood oxygen is a critical component of the TME and is significantly linked to tumor immune response, angiogenesis, metabolism, and

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