Titlebook: Hypertension and the Brain as an End-Organ Target; Hélène Girouard Book 2016 Springer International Publishing Switzerland 2016 aging.brai

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Hélène GirouardFirst overview to look at the effects of hypertension on the brain.Looks at both humans and animal models.Insight from studies using a variety of in vivo and in vitro methods

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978-3-319-79815-8Springer International Publishing Switzerland 2016

myelography

A Systematic Review of Reviews to Examine the Association Between Hypertension and Cognitive Impairsessed the methodological quality of the included reviews using the .ea.urement .ool to .ssess Systematic .eviews (AMSTAR) tool...: We included four meta-analyses and one systematic review. Results suggested small associations between hypertension and global cognition, episodic memory, and attention

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Hypertension and Age-Related Cognitive Decline,rtensive drug treatments report diverging results, but tend to suggest that treatment might be effective in preventing cognitive decline associated with age. Together, findings summarized here suggest that hypertension is an important factor that has a worsening effect on cognition as people age, an

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The Effects of Hypertension on Cerebral Artery Structure and Function, and Cerebral Blood Flow,leads to increases in myogenic tone and impaired dilation. Dysfunction of ion channels, including calcium-activated potassium channels and transient receptor potential (TRP) V4 channels, has also been associated with impaired endothelial function in hypertensive models. Understanding the mechanisms