Titlebook: Human Mast Cells; Ann M. Dvorak Book 1989 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH

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Ultrastructure of Human Basophils,76a, b, 1980e, 1981a, b, 1982, 1983a, c, d, 1985b; Dvorak and Dvorak 1975; Findley et al. 1981; Fox et al 1984; Galli et al. 1983, 1984; Ishizaka et al. 1985; Peters et al. 1987). These diagnostic features include polylobed nuclei with a condensed chromatin pattern, surface architecture which consis

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In Vitro Studies of Human Mast Cells,identifiable in electron micrographs by their shape and variable osmiophilia and also because they lack a limiting membrane. Regular substructural internal patterns are absent from lipid bodies. Focal lucent areas and vesicular structures can sometimes be seen within lipid bodies (Fox et al. 1985).

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Summary,ls in a variety of tissues in situ. We have reviewed these contributions and provide here unified information necessary for the recognition of the variable images presented by human mast cells and the substructural patterns of their granules. These studies in aggregate provide sufficient and necessa

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Concluding Remarks,In this review we have discussed aspects of human mast cell biology that have recently been illuminated by morphologic analysis. These findings build on a considerable ultrastructural literature which we also review here in order to present an integrated view of human mast cell ultrastructural morphology.