Titlebook: Vogel and Motulsky‘s Human Genetics; Problems and Approac Friedrich Vogel,Arno G. Motulsky Book 19973rd edition Springer-Verlag Berlin Heid

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Gene Action: Genetic Diseases,The topics discussed earlier such as the structure of the genetic material and Mendelian segregation are interesting scientifically because they help in solving this basic question. In Chap.6 Mendelism is described as the central paradigm of genetics. Thus, a Mendelian mode of inheritance for a cert

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Gene Action: Developmental Genetics,he lessons regarding the genetic basis of embryonic development, however, have been much less satisfactory. The genetics of development is only beginning to be charted on the map of our knowledge of molecular genetic mechanisms, but studies with methods from molecular genetics are now starting to el

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Mutation: Spontaneous Mutation in Germ Cells,been possible if no change in genetic material had ever occurred. Since there is good evidence that all living beings on our planet have a common origin, genes as the carriers of genetic information must have the capacity for occasional alterations. Such changes are indeed observed; they are called

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Mutation: Somatic Mutation, Cancer, and Aging,saic. Mosaics are individuals with a mixed cell population. In the simplest situation a normal cell population and a mutant cell population may coexist in a single individual. Often such different populations exist side by side. In fibroblasts — and possibly in other cell types — there is extensive

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Mutation: Induction by Ionizing Radiation and Chemicals,n though we know that some conditions — such as parental age — may enhance the probability of mutation. This probability increases under the influence of certain agents, such as energy-rich radiation and a number of chemicals. Since human beings in their normal environments are exposed to a variety

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Population Genetics: Description and Dynamics,ons, selection, migration, and chance fluctuation of gene frequencies. All these factors together determine the genetic population structure. Knowledge of population genetics is useful for many purposes. For example, it provides a basis for understanding the epidemiology of genetic diseases and help

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