Titlebook: Hormonal Carcinogenesis II; Proceedings of the S J. Jonathan Li (Professor of Pharmacology, Toxicol Conference proceedings 1996 Springer-Ve

Arctic

Breast Susceptibility to Carcinogenesis; and they are composed of clusters of 6 to 11 ductules per lobule. Lobules type 2 evolve from the previous ones and have a more complex morphology, being composed of a higher number of ductular structures per lobule. They progress to lobules type 3 which are characterized by having an average of 80

Simulate

Hormones, Growth Factors, and Gene Expression in Preneoplasias of the Mouse Mammary Glando the cleared fat pads of syngeneic mice, resulting in stable hyperplastic outgrowth lines (1,4). Regardless of the etiology of the alveolar hyperplastic outgrowth lines, the essential biological properties are similar for the different lines. The outgrowth lines are essentially clonal derivatives o

ALERT

J. Jonathan Li (Professor of Pharmacology, Toxicol

神刊

Introductory Remarks. I am a Program Director in the Chemical and Physical Carcinogenesis Branch, which is part of the Division of Cancer Etiology, National Cancer Institute of the United States National Institutes of Health, the NIH. As most of you are aware, the NIH supports intramural, multidisciplinary research pro

Sputum

過多

Symposium Presentationinteracting with the genetic material, leading to formation of DNA-adducts and other chemical insults. A key enzyme in this scenario is cytochrome P-450, which can carry out a multitude of chemical reactions whereby both xenobiotics and sometimes endogenous compounds may be transformed into highly r

空洞

結(jié)果

CUMB

國家明智

Nucleocytoplasmic Shuttling of Estrogen Receptors is Blocked by “Pure Anti-Estrogens”and (1). As with other steroid receptors, in the absence of ligand the estrogen receptor is found in an oligomeric complex that is unable to bind to DNA (2–4). Following hormone binding, the complex is dissociated to allow receptor dimerization, high-affinity DNA binding, and transcriptional activat