Titlebook: Histone Mutations and Cancer; Dong Fang,Junhong Han Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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Overview of Histone Modification,hat histone modifications, DNA methylation, and RNA-based mechanism are the main means of epigenetic control. In this chapter, we will focus on the general introductions of epigenetics, which is important in the regulation of chromatin structure and gene expression. With the development and expansio

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The Histone H3 Family and Its Deposition Pathways, chromatin organization contributes to the regulation of all DNA template-based reactions impacting genome function, stability, and plasticity. Histones and their variants endow chromatin with unique properties and show a distinct distribution into the genome that is regulated by dedicated depositio

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Histone H3G34 Mutation in Brain and Bone Tumors,34R/V mutation have a generally adverse prognosis, whereas giant cell tumors of bone are rarely metastatic benign tumors. G34 mutations possibly disrupt the epigenome by altering H3K36 modifications, which may involve attenuating the function of SETD2 at methyltransferase. H3K36 methylation change m

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de. Southern Ocean ? sheries and in particular the Patagonian Tooth? sh, have been targeted by IUU ? shers. The text examines the response to the persistent problem of IUU ? shing in 1 the Southern Ocean, by CCAMLR, as the appropriate RFMO, and Australia, a State with vested interests in the Souther

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