Titlebook: Handbook of Blood and Blood Products; S. Ghosh Textbook 1988Latest edition S. Ghosh 1988 adverse reactions.blood.cell.immunoglobulin.manag

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Essential Transfusion Serology,An understanding of certain aspects of transfusion immunology and serology is essential to all clinicians involved in using transfusion therapy. This chapter is intended to give a basic working knowledge of the subject.

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Blood Products: Platelet and Granulocyte Preparations,Each unit contains platelets harvested from one unit of fresh whole blood. An average unit contains between 0.5 and 1 × 10. platelets suspended in about 50 ml of plasma. It also contains some leucocytes and red cells.

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Blood Products: Immunoglobulin Preparations,This is prepared from plasma pooled from a large number of donors. Antibody levels against stated viral and bacterial antigens are usually too low to meet pharmacopoeial standards. There is considerable variation in the content of specific antibodies between different preparations and between different batches of HNI.

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Special Transfusion Situations,An emergency transfusion can be defined as a transfusion which is immediately necessary for the survival of the patient. It is usually necessary for those who have suffered excessive acute blood loss and those who present with hypovolaemic shock requiring immediate volume replacement.