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11#
發(fā)表于 2025-3-23 11:22:09 | 只看該作者
D. Wild,K. Eckhardt,E. Gocke,M. T. Kinginteracting with a PDZ domain of the postsynaptic scaffold protein PSD-95 suggests that the α. subunit directs a membrane association of this isoform. The interaction with PSD-95 locates the α.?. isoform in close proximity to the NO-generating NO synthase thereby enabling the NO sensor to respond to
12#
發(fā)表于 2025-3-23 16:58:01 | 只看該作者
13#
發(fā)表于 2025-3-23 19:27:23 | 只看該作者
Biochemistry and physiology of the natriuretic peptide receptor guanylyl cyclases, peptide ligands and mechanisms of regulation serve as prototypes for understanding the function of other particulate GC. Activation of this enzyme by its ligand is a complex process requiring oligomerization, ligand binding, KHD phosphorylation and ATP binding. Gene knockout and genetic segregation
14#
發(fā)表于 2025-3-24 00:41:07 | 只看該作者
15#
發(fā)表于 2025-3-24 02:29:28 | 只看該作者
16#
發(fā)表于 2025-3-24 09:43:46 | 只看該作者
17#
發(fā)表于 2025-3-24 12:20:21 | 只看該作者
Ultracytochemistry as a tool for the study of the cellular and subcellular localization of membranee cyclase in secretory processes. Finally, S 100B and S100A1 were found to colocalize with membrane-bound guanylate cyclase on photoreceptor disc membranes and to stimulate enzyme activity at these sites in dark-adapted retinas in a Ca.-dependent manner. The results of these analyses are discussed i
18#
發(fā)表于 2025-3-24 16:54:09 | 只看該作者
19#
發(fā)表于 2025-3-24 19:39:26 | 只看該作者
20#
發(fā)表于 2025-3-25 02:30:17 | 只看該作者
Retinal diseases linked with photoreceptor guanylate cyclase,he biochemical effect of the mutation and its phenotypic manifestation was provided for only one LCA 1 mutation, F514S. This was followed by biochemical analyses of the consequences of the CORD6-causing mutations. Here, an overview on the existing results and a discussion of the possible physiologic
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