Titlebook: Glycosignals in Cancer; Molecular Assembly a Koichi Furukawa,Minoru Fukuda Book 2023Latest edition Springer Nature Singapore Pte Ltd. 2023

Inelasticity

https://doi.org/10.1007/978-3-7091-3638-6lycosylation is regulated by the cellular expression profile of enzymes regarding glycan and substrate synthesis and the cellular metabolism reflecting cellular status and microenvironments. In the disease process, the glycan synthesis pathway is altered, and aberrant glycans can be generated. Sialy

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https://doi.org/10.1007/978-3-662-00275-9ed by sialic acid–containing glycoconjugates. The lectin was subsequently found to belong to the vertebrate-secreted ribonuclease family, and cSBL exhibits ribonuclease activity as well as remarkable antitumor effects. Recent studies have shown that cSBL exerts antitumor effects in vitro and in vivo

漂亮

,Verbandslehre und ?Erste Hilfe“,of glycolsphingolipids have been largely elucidated via glyco-remodeling cells and animals. The progress in these glycobiology techniques has enabled us to understand the roles of “tumor-specific” carbohydrates during these 3 decades. Tumor antigens recognized by host immune systems of cancer patien

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Hans-Werner Klempt,Franz Benderroblastoma, which comprises ~50% of neuroblastoma, is dismal. Abundant expression of disialoganglioside GD2 antigens is a feature of neuroblastoma. The success of immunotherapy targeting the GD2 antigen with dinutuximab has fueled the interest in developing improved immunotherapeutics including huma

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Substantial Basis for Glyco-Assembly: Siglec7 and Synthetic Sialylpolymerslecs, on their cell surface. These self-non-self discriminating machineries give not only an advantage to the host cells in innate immune system but also a disadvantage because they allow cancer cells to escape from the immune cells. Siglec7 is one of such machineries predominantly expressed in natu